Exclusion testing for extraneous agents involves propagation of target agents in a range of sensitive culturing systems.
Bacterial, Fungal and Protozoan culture systems
Vero Cell Monolayers
General assays for the detection of inclusion bodies and multinucleated cells are performed by visual observation of Cytopathic Effect (CPE) and H&E staining, or haemadsorption of guinea pig and chicken blood on cell monolayers.
Heamadsorption Guinea pig blood cells
Hematoxylin and Eosin stained cells
